The first cannabinoids were researched at the beginning of the 19th century – but it was not until the groundbreaking discovery of the endogenous cannabinoid receptor system in the 1980s that the foundation of CBD research was laid.
The complex system that is part of the nervous system helps regulate various processes in the body—a revolutionary finding – which set the starting signal for many investigations. Since then, drugs based on hemp have been intensively studied.
Also, you should know that CBD is legal in Europe and in the UK and that you can order the best CBD flowers, CBD oils, and other CBD products online. Besides, if you want to learn about the boom in sales of legal CBD in Europe, click here.
Science and CBD
Did you know that in 2011 an extract containing cannabis was approved for medicinal purposes in Europe for the first time?
It has now been well established that CBD may have complementary therapeutic benefits for various ailments. Although several conclusive studies with CBD are still needed, the initial basic research provides a good overview.
“The benefit of cannabinoid therapy for many medical indications has been demonstrated by controlled studies using mostly standardized and/or synthetic cannabinoid preparations. Therefore, the use of these preparations can be useful for different topics,” according to the Federal Medical Association, the National Association of Statutory Health Insurance Physicians, and the Drug Commission of the German Medical Association.
Here are some interesting studies conducted to show the many CBD benefits on the body and mind:
CBD accompanying negative sensory perceptions
The endocannabinoid system and migraines
- Conclusion: It could be shown that the endocannabinoid system, or ECS for short, is centrally and peripherally involved in the processing of pain signals. The results indicate that activation of the ECS could be a promising tool in pain reduction.
CBD for sleep support
Hypnotic and antiepileptic effects of cannabidiol
- Conclusion: The double-blind study with 15 subjects suffering from sleep problems showed a significant improvement in sleep duration. The placebo showed no corresponding effects.
CBD as a supplement for skin complaints
Cannabinoid signaling in the skin: therapeutic potential of the “cannabinoid” system
- Conclusion: The endocannabinoid system is also involved in skin barrier formation and regeneration. It influences several aspects of skin biology. A dysregulation has been linked to widespread skin complaints. Cannabinoids can therefore be a powerful tool in complementary therapy for the skin.
CBD as a neurodegenerative support
Cannabidiol in patients with seizure disorders associated with Lennox-Gastaut syndrome (GWPCARE4): a randomized, double-blind, placebo-controlled phase 3 study
- Conclusion: In a randomized, double-blind, placebo-controlled study conducted at 24 clinical centers in the USA, the Netherlands and Poland, we evaluated the efficacy of cannabidiol as adjunctive therapy for seizures in patients with treatment-resistant Lennox-Gastaut syndrome. Cannabidiol proves to be a complementary, effective therapy with good tolerability. Long-term efficacy and safety will be evaluated in the open-label extension of the study.
CBD and seizure
Cannabidiol improves seizure frequency and severity and reduces adverse events in an open-label prospective add-on study.
- Conclusion: The results already showed significant improvements after 12 weeks. The response was sustained over the 48-week treatment period. The results are fascinating because the group included patients with a specific diagnosis and subjects of all ages with different types. Even after 24 months, there was a sustained reduction in seizure frequency and severity. In addition, the complementary therapy with CBD led to a sustained decrease in the side effect profile.
Where can I find other exciting studies?
In our excerpt, you will find studies that have been carried out with and on humans. However, numerous studies are carried out on animals or cell cultures. These cannot be transferred directly to humans and only provide indications.
Therefore, in almost every CBD study, you will find the postscript “Further investigations are necessary”.
However, since CBD research is still relatively young, it holds enormous potential.
The studies also show that the CBD boom means inferior CBD oils are also in circulation. The low quality is reflected in lower effectiveness. So reaching for high-quality oils with a high CBD content is worthwhile.
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